Administering medications to veterinary patients can be a challenging task for owners. Palatability issues with bitter drugs is very common and masking the taste of these drugs can be difficult. The logistics of simply giving an oral medication to pets often exacerbate existing challenges. However, delivering medications through the skin using permeation-enhancing vehicles may provide welcomed options for veterinarians and their patients, and serves as a prime example of how compounding shines by offering alternative delivery systems.