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Technical Report: Efficacy of PracaSil™-Plus in the Improvement of Scar Appearance - Part 2

Introduction:

PracaSil-Plus is a proprietary anhydrous silicone base designed to be applied topically for scars and other skin conditions (PCCA, 2014). Silicones have been widely used for their occlusive and hydration properties, which are essential in scar management (Widgerow et al., 2000; Mustoe, 2008). PracaSil-Plus also contains Pracaxi oil, extracted from the oilseed plant Pentaclethra macroloba, which has several medicinal applications including skin regeneration and healing (Crespi and Guerra, 2013; Costa et al., 2014). PracaSil-Plus may be used alone or as a base for the incorporation of different active substances (PCCA, 2013).

Abstract:

The efficacy of PracaSil-Plus in the improvement of scar appearance vs. a reference commercial scar product was evaluated by visual and instrumental methods in an eight-week, randomized, double-blind, controlled study. PracaSil-Plus outperformed the reference scar product and showed superior qualitative and quantitative improvements in scar color, smoothness and roughness.

Conclusions:

PracaSil-Plus, a proprietary base containing silicones and Pracaxi oil, showed superior qualitative and quantitative improvements in scar color intensity, texture smoothness and roughness. PracaSil-Plus outperformed the reference scar product for the improvement of scar appearance.

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